Starting date :
Dec. 2023 > Nov. 2028
Lifetime :
60 months
Program in support :
HORIZON-HLTH-2023-TOOL-05
Status project :
In progress
CEA-Leti's contact :
Project Coordinator :
University of Twente (UT)
Partners: -
UNIVERSITEIT TWENTE
- E.P.O.S. IASIS RESEARCH AND DEVELOPMENT LTD
- XSENSIO SA
- ECOLE POLYTECHNIQUE FEDERALE DE
LAUSANNE
- STICHTING IMEC NEDERLAND
- CHARITE - UNIVERSITAETSMEDIZIN BERLIN
- INSTITUT GUSTAVE ROUSSY
- FONDATION HOPITAL SAINT JOSEPH
- COMMISSARIAT A L ENERGIE ATOMIQUE ET AUX ENERGIES
- DEN INSTITUTE
- UNIVERSITATEA POLITEHNICA DIN BUCURESTI
Targeted Markets :
Health, MedTech companies, medical devices
Keywords :
Point-of-care system, real-time monitoring of biomarkers,system integration for medical devices, low-power electronics, microneedle technology, microfluidics, wearable sensor, lung cancer, cardiac diseases, clinical validation, AI data processing, intuitive extended reality
Credit photo :
CEA-Leti
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Stakes
The central goal of the RealCare Project is to enable rapid medical decision-making, with a specific focus on two major medical use cases: cancer (real-time monitoring in the surgery room and intensive care unit) and cardiac diseases (monitoring at the edge of intensive care unit to normal ward and home monitoring of transplanted patients or suffering from heart failure)..
Objectives
- RealCare is a cutting-edge research initiative focused on developing and validating next-generation point-of-care (PoC) systems that detect essential biomarkers in human biofluids in real-time. These systems are designed to be compact, energy-efficient, and integrated with extended reality interfaces, with a specific emphasis on cancer and cardiac diseases in demanding clinical settings.
RealCare's approach includes advanced biomarker detection technologies, such as microfluidics and new generations of microneedles, label-free electrochemical biosensors using 2D materials, optical sensors utilizing CRISPR, biological amplifiers combined with fluorescent microscopy, and scalable SPR with energy-efficient electronic readouts, AI data processing, and wireless communication units.
Additionally, RealCare will design portable, interoperable, and adaptable PoC systems that integrate the biomarker detection technology with vital sign monitoring, including advanced data analytics and AI methods. The initiative also focuses on developing intuitive extended reality interfaces, such as augmented and virtual reality, to visualize biomarker data in realtime and facilitate rapid medical decision-making in integrated in-care environments and workflows.
Rigorous clinical validation studies will be conducted in relevant clinical settings, including the surgery room, ICU, and patient's home, to ensure accuracy, reliability, usability, and impact on patient outcomes.
Impacts
- Better health care and quality of life through compact, energy efficient point-of-care systems for cancer and cardiac diseases. Promising lab-to-market paths with the potential for significant societal and economic impact
Societal: better and fairer health care, greater satisfaction with health care quality, specific emphasis on cancer and cardiac diseases
Scientific: Advanced expertise as a basis for further theory development, integration and validation
Economic: lower costs by avoiding superfluous tests and treatments, saved time and resources, workplaces generated
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